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UF creating mRNA brain cancer vaccine

Discussion in 'Too Hot for Swamp Gas' started by demosthenes, May 4, 2024.

  1. ncargat1

    ncargat1 GC Hall of Fame

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    Just a guess, but adolescents often have under developed immune systems. Children barely have immune system development. I wonder that if they can provoke an immune response in a child, it should be even better in older adults??
     
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  2. QGator2414

    QGator2414 VIP Member

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    All depends on the drug. That said…this would be better classified as a mRNA Brain Cancer Therapy. But you do you.
     
  3. OklahomaGator

    OklahomaGator Jedi Administrator Moderator VIP Member

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    I thought about deleting some posts but instead I will just say this:

    This is not a COVID thread, keep it that way. Future posts that I or other mods think are covid related will be deleted.
     
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  4. gatorpa

    gatorpa GC Hall of Fame

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    That’s not correct if it was infants would not get vaccines as they would be useless.

    Older people don’t have as good an immune response which is why they are more susceptible to things like Influenza, pneumonia, covid.
     
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  5. G8trGr8t

    G8trGr8t Premium Member

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    It is a thread about medical advancements using many of the same tools used to create the covid vaccine. One cannot be intellectually honest and support one mrna advancement but not the other
     
  6. gatorpa

    gatorpa GC Hall of Fame

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    That all depends, for example not all stains are equal despite them having a similar mechanism of action. Same goes for most all classes of medications.
     
  7. Gatorrick22

    Gatorrick22 GC Hall of Fame

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    I hope they succeed, but I will not be trying it anytime soon.
     
  8. GatorJMDZ

    GatorJMDZ gatorjack VIP Member

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    True. Some Tide alone will remove, some require OxiClean.
     
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  9. GatorRade

    GatorRade Rad Scientist

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    My post was mostly a joke Q. Dan’s post basically called you stupid, so I understand why you responded as you did. I think that post would have provoked someone regardless of which issue it concerned.
     
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  10. co_gator89

    co_gator89 GC Hall of Fame

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  11. ncargat1

    ncargat1 GC Hall of Fame

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    Infants get vaccines to kick-start their adaptive immunity. That is why almost all of them are multi-part given over many months and often even years apart. I am no expert in the human immune system, but I have read enough to understand that. Most children have their immunity passed to them through the placental barrier, and as a result do not have active immune systems at that age. As those antibodies fade over the first 4-6 months of life, the innate immune system of the child begins developing. Finally, that adaptive system develops fully over the first 4-12 years of life.

    Elderly have very well developed immune systems. However, they are likely failing as cellular system begin to fail due to age. That makes them inefficient, not poorly developed.

    Further, if you were to want to take this advancement and transform it from a treatment for the individual to a wide spread vaccine, at some point you would to study the effects in as naïve of an immune system as possible. For example, 2018 literature suggested that by roughly 60 years old, the body has nearly exhausted its ability to produce naïve B and T cells. Thus, if people have never been vaccinated by age 60, a much different strategy for protecting people from disease is needed. It is quite possibly this barrier that researchers wish to avoid contending with.
     
  12. AgingGator

    AgingGator GC Hall of Fame

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    Thank you for your restraint. I’m proud of you. The stupidity in your multiple previous comments relative to the anti vac crowd is well documented here. I’m glad you opted not to embarrass yourself further. If you can continue with this restraint you may actually be seen as someone who posts with reason and intelligence.
     
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  13. danmanne65

    danmanne65 GC Hall of Fame

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    Is responding to this worth the vacation from the sight I would get? Let me think on this.
     
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  14. AgingGator

    AgingGator GC Hall of Fame

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    Go for it! More people than you know could use the break!
     
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  15. danmanne65

    danmanne65 GC Hall of Fame

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    Ha ha. You think you know what I would say just say it to yourself for me. Feel free to add any invectives you like.
     
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  16. QGator2414

    QGator2414 VIP Member

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    I know some here have it out for me regardless. And others have blocked/ignored me. But this was a good thread. It is fantastic science and medicine.

    What stinks is that in todays world certain words trigger responses (or in my case questioning). mRNA has been on the cancer front for decades. And imo I believe we could see some amazing breakthroughs to at a minimum increase and lengthen the quality of life for those that unfortunately have to deal with such a terrible disease.

    Reality is this is more of a Cancer therapy. At the same time it fits the definition of a vaccine. It is amazing stuff and hopefully develops into a drug/therapy to if not cure…enhance the life of those affected by a terrible disease!
     
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  17. jhoge53_

    jhoge53_ Junior

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    Proud our university is involved in this research to fight cancer. My daughter was diagnosed with leukemia (AML) in 2019. She underwent chemo at Stanford Medical. My son was a donor match (1 chance in 4). After taking blood from my son they treated it lasers and magnets to reduce transplant reactions. The transplant was successful. The science developed over decades allowed the doctor's and nurses at Stanford to save her life. It is about science, not the invisible man some people worship.


























    p
     
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  18. danmanne65

    danmanne65 GC Hall of Fame

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    Absolutely none of my business and feel free not to answer but it was a bone marrow transplant, wasn’t it? I am glad your daughter is doing better and congratulations on raising a son who knows what’s important. Give them both a hug for me at your next opportunity.
     
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  19. WarDamnGator

    WarDamnGator GC Hall of Fame

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    This is just begging ... begging ... for a smart ass comment. But I'll be nice.
     
  20. Gatorrick22

    Gatorrick22 GC Hall of Fame

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    Nice? It's not in your nature to be nice. What you mean to say you will not post your normal hated simply because I said I will not try that drug anytime soon.
     
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