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Moderna's mRNA Skin Cancer Vaccine Shows Durability for 3 Years

Discussion in 'Too Hot for Swamp Gas' started by ncargat1, Dec 14, 2023.

  1. ncargat1

    ncargat1 GC Hall of Fame

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    This is just barely scratching the surface of where we will be able to get to in 10 years with mRNA technology helping to unleash our bodies immune system against cancers. Note - this is vaccine targeted at lower the incidence of future occurrence or spread, not a cure. No less impressive however.

    Experimental cancer vaccine, combined with immunotherapy, continues to show benefits against melanoma, trial shows | CNN
     
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  2. danmanne65

    danmanne65 GC Hall of Fame

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    I am all in on the research. I just wonder how all the know nothings will attack this advance.
     
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  3. GatorNorth

    GatorNorth Premium Member Premium Member

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    As a 2 time Melanoma patient this advance is very good news.
     
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  4. channingcrowderhungry

    channingcrowderhungry Premium Member

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    Saw a funny comic last week that I can't post because an Eff bomb. The sun is coaxing someone outside offering Vitamin D and Serotonin. Then we they go outside he hits em with some skin cancer
     
  5. tampagtr

    tampagtr VIP Member

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    Excellent news. So much promise in mRNA.
     
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  6. VAg8r1

    VAg8r1 GC Hall of Fame

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    Agree as someone who had a melanoma (fortunately stage 0), a squamous cell carcinoma and 5 or 6 basal cell carcinomas it's very good news. I've been paying the price for hours in the South Florida sun without sun screen 50 years earlier.
     
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  7. ncargat1

    ncargat1 GC Hall of Fame

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    Well, they cannot use the "it re-writes your DNA" BS, since the replication errors that lead to the tumors are, in fact, re-writing your DNA.
     
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  8. duggers_dad

    duggers_dad GC Hall of Fame

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    upload_2023-12-14_10-20-56.jpeg
     
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  9. danmanne65

    danmanne65 GC Hall of Fame

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    When did logic and facts matter to anti vax ers?
     
    Last edited: Dec 14, 2023
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  10. GatorNorth

    GatorNorth Premium Member Premium Member

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    Same, but central Florida. And I’ve had numerous of each as well.

    What were we thinking lathering up with cooking oil and staying in the sun for 8-10 hours a day roasting like a Kenny Rogers rotisserie chicken?
     
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  11. GatorNorth

    GatorNorth Premium Member Premium Member

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    Waiting for someone to jump on here and say “there’s no such thing as cancer”.
     
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  12. duggers_dad

    duggers_dad GC Hall of Fame

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    My dad died of cancer when I was ten. But there are questions about a vaccine … for cancer ? To go along with the myriad other vaccines were encouraged to take.
     
  13. GatorJMDZ

    GatorJMDZ gatorjack VIP Member

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    My bout with skin cancer resulted in me letting my season tickets go and turned me into a vampire....I no longer do the sun. I sat in the dermatologist's office reading all those pamphlets about skin disorders as I was waiting and the dominating cause was sun exposure. All those days of life guarding, teaching swim lessons, teaching SCUBA lessons and diving, I never wore sunscreen. I stupidly thought if I didn't burn, I wasn't hurting anything. My Mom used to get furious at me over that and I was 100% wrong.

    PSA: If you get skin cancer, insist on Mohs micrographic surgery, even if your insurance doesn't cover it. With Mohs, the doctor removes the bad spot and a surrounding ring of what they hope is healthy skin. They have lab facilities right there to test it and they keep going until they no longer find cancer cells.

    I went it with a sore the diameter of a pencil eraser on my ear that just wouldn't heal. I paid for Mohs and it was not until after the 4th attempt that it was finally clear. By that time, half the skin on the front of my ear had been removed (replaced with a skin graft harvested from behind my ear.) Absent that type of testing, the doctor is just guessing/hoping. I know a few people who had to go in for more surgery because they didn't get it all and it came back.
     
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  14. GatorNorth

    GatorNorth Premium Member Premium Member

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    Mohs is the required surgical treatment for squamous, took 3 times to get my first one.

    It’s not done for melanoma or basal cell due to the nature of the cancer, which isn’t conducive for whatever the Mohs onsite analytical process is (as I’ve been told).
     
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  15. GatorNorth

    GatorNorth Premium Member Premium Member

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    Truly sorry for the loss of your dad at such a young age, but I would welcome a vetted vaccine for melanoma that minimized recurrence risk. 2 bouts for me and 2 friends who died from it.
     
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  16. VAg8r1

    VAg8r1 GC Hall of Fame

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    I've had two Mohs procedures, one for a basal cell carcinoma on my nose, the other for a basal cell lesion on my scalp. The procedure on my nose required a skin graft and now I have to shave the bridge of my nose around once a week. My melanoma was removed through a procedure called staged excision. Somewhat similar to Mohs but done in two separate procedures, the first to determine the margins of the cancer, the second to remove it. Also required a skin graft. The lesion was on my cheek by the way.
     
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  17. GatorJMDZ

    GatorJMDZ gatorjack VIP Member

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    Mine was basal, but they actually found a few squam cells, too. The doctor said it is highly unusual to have both types at the same site.
     
  18. duggers_dad

    duggers_dad GC Hall of Fame

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    Indeed, I had a young friend who died of melanoma recently. Her treatment regimen ravaged her body.

    Same for my father. I will always wonder whether their ordeals would have been ‘less bad’ without the treatments.

    But, if a shot is a distinct improvement, I don’t blame people for taking it.
     
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  19. littlebluelw

    littlebluelw GC Hall of Fame

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    Had a melanoma cut out this past summer. Hopeful for this advancement in treatment.
     
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  20. GratefulGator

    GratefulGator GC Hall of Fame

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    Some people like, "I ain't putting no mRNA in my body."
    Then when they get the cancers, be all like "Gimme some mRNA!"
     
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