Covid-19: Treatments, Cures, and Vaccines

CDC Director signs off on Pfizer/BioNTech shots for children 5-11 years old.

Coronavirus Disease 2019

 

My mental health issues are finally paying off!!

 

https://www.cnbc.com/2021/11/04/merck-oral-covid-pill-approved-by-uk-in-world-first.html

 

The mentally ill will inherit the earth.

 

Well...They already govern it...so. ¯\_(ツ)_/¯

 

Pfizer release interim data on their anti-viral pill and summary of the data indicated that the pill reduced the risk of hospitalization by 89%. The company plans to release additional details and data through a peer reviewed paper, as well as part of the FDA EUA request. The yet unnamed drug is a protease inhibitor and interferes with ability of the virus to replicate itself. The plan is pair this drug with an older drug, used to combat HIV, Ritanovir (this drug slows your bodies ability to breakdown the other drug, so it stays in your system longer and continues to work.

Pfizer says its experimental pill reduces risk of hospitalization, death from Covid-19 - CNN

 

Please god let this be the end of this shit show.

 

Wonder if this will generalize to other viruses

 

Protease inhibitors are part of the cocktail that slowed the spread of HIV in the Western countries.

 

I know that and saw it above. But it is now being applied to an infectious disease that passes by aerosol.

 

Not sure why that is relevant? My understanding is that protease is an enzyme that aids in the cleaving of the proteins necessary for virus particles to copy themselves. By blocking that enzyme from doing its job, the virus cannot copy itself. As a non-virologist or biologist even, not sure why the method of transmission would relevant here?

 

Pfizer booster shot could offer protection for 9-10 months — initial data

Pfizer’s booster COVID-19 shot is effective for 9 – 10 months and maybe even longer, according to preliminary data from Israeli research leaked to Channel 12 news on Sunday.

The booster shot yields more antibodies, and the antibodies are also better at preventing the disease, the channel quoted people involved with the study as saying.

By analyzing the antibody levels, researchers have concluded that the third shot could be effective for 9 – 10 months, or even longer, the researchers predicted.

 

Accorin

According to the different virologists and immunologists that I listen to via podcasts, the synthetic molecule based virus that Novavax created is an excellent vaccine that is a strong candidate for future boosters. Because it replicates more than just the spike, it provokes a more broad immune response than the mRNA vaccines.

The big issue with filing for the EUA in the United States has been its manufacturing chain has had problems. Part of the FDA review is your manufacturing controls and ability to produce at volume and in control. This is what has delayed their application.

The 90% efficacy in Phase 3 trials was nothing to sneeze at.

 

Friend if mine got that in the trials

 

Supposedly, the safety profile and the lack of severe reactogenicity make this ideal for future boosters. Hope your friend did well after the shot.

 

Final data showed Molnupiravir much less effective than early reports indicated. Regulators are also worried that this drug may actually lead to new variants.

As my non-medical understanding goes:

Molnupiravir works by changing the chemistry involved in viral replication inducing "copy errors" that eventually renders the virus unable to continue to replicate.

By contrast, the Pfizer drug Paxlovid, modifies the enzymes released by the virus that are needed for viral replication. Thus preventing replication. It is likely to be paired with a second drug used with protease inhibitors in HIV patients. The second drug, Ritanovir merely slows down the bodies metabolism of the protease inhibitor, so it stays active in the body for a longer period of time.

Merck's COVID-19 pill significantly less effective in new analysis

 

Also, for anyone interested in joining a trial studying the effects of Ivermectin and/or Fluvoximine, there is a trial named COVIDOUT, run out of the University of Minnesota that is enrolling. You only need to be 18-85 and have had a positive Covid test within the past 3 days. This will be the largest trial study of Ivermectin and Fluvoximine conducted in the United States to date.

If you are unfortunate enough to contract COVID, here is the contact information for the trial.....

Home | COVID-OUT: Outpatient Treatment for SARS-CoV-2 Infection, a Factorial Randomized Trial

 

Former Pfizer Employee Says COVID-19 Vaccine Causes Recipients to Become More Susceptible to the Virus – Fox26Newshenry

According to the whistleblower, “So, when they weren’t injected, their infection rate was 1.3% and when they got injected, it was 4.34%. It went up by over 300%. They had less infection when they had no protection. So, that’s a problem.”

Kingston said, “if you have two doses of Pfizer, your rate for getting infected [with COVID-19] increases over time.”

Leading to a discovery the biotech analyst called “super alarming,” the report looked exclusively at the placebo group, comparing their rate of infection in the first four months, when they had no protection, to the four months following their injections with the Pfizer product.

During that initial placebo period, the document reports that the infection rate of this group was “12.6 cases per 1,000 person-years,” which equates to a 1.3% infection rate. Following their injections, there were “43.4 cases per 1,000 person- years” or a 4.34% infection rate.

“So, when they weren’t injected, their infection rate was 1.3%, and when they got injected, it was 4.34%. It went up by over 300%,” Kingston observed. “That 300% increase is a correlation, it’s not an anomaly.”

Thus, she summarized, “They had less [COVID-19] infection when they had no protection [from the Pfizer shots]. So, that’s a problem.”

While correlation does not prove causation, looking at relevant global data, we find a worldwide trend of high rates of infections, hospitalizations, and deaths among the vaccinated.

This phenomenon of rising cases occurring in association with high vaccine uptake has become a universal trend while there has also been a correlation between COVID-19 vaccine campaigns and rising death rates from the disease as well.

Summarizing the findings of the Pfizer study in the FDA briefing document itself, Renz explained to his large live and streamed audience, “It says if you get the Pfizer vax, you’re more likely to get COVID. More likely! It says it right there.”