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Covid-19: Treatments, Cures, and Vaccines

Discussion in 'Too Hot for Swamp Gas' started by exiledgator, Apr 10, 2020.

  1. duchen

    duchen VIP Member

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    ASR’s Zeneca was rejected because of the clotting risk. Low as it is, it is too high.
     
  2. WC53

    WC53 GC Hall of Fame

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    Need the Yeti and Salt life versions. Comes with a free coupon and glow in the dark tattoo.

    We could charge enough to pay for all health care
     
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  3. ursidman

    ursidman VIP Member

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    Washington County inmates refusing Ivermectin; state investigating jail doctor

    A jail in Arkansas has been treating inmates with Ivermectin as part of its routine to treat and prevent Covid.
    FAYETTEVILLE -- Prisoners in the Washington County jail said Thursday they're refusing to take Ivermectin after learning the drug was part of the covid-19 treatment program at the jail.

    "That changed last night," Edrick Floreal-Wooten said during a telephone interview. "Last night they asked us, 'Do you want to take the pill or not?' I said, 'No ma'am, I do not.' There are 20 other inmates in this pod they've been giving it to. Everyone is refusing to take it."
    I figured I was in here to serve my little 90-day commit," he said. "I didn't figure Washington County was going to make me an experiment and use drugs the CDC didn't recommend. I'm not livestock. I'm a human being."
     
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  4. gatorchamps960608

    gatorchamps960608 GC Hall of Fame

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    Someone is making bank on this witch potion.
     
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  5. tampagtr

    tampagtr VIP Member

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    Humor

     
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  6. duchen

    duchen VIP Member

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    good one!
     
  7. l_boy

    l_boy 5500

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    I'd hit it! / Qgator
     
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  8. ncargat1

    ncargat1 VIP Member

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    Latest data release by the CDC :

    1. Through the end of July 2021, in the United States, the mRNA vaccines continue to prevent severe disease and hospitalization at a 94% rate for people under 75, and at a rate of 80% of 75. Despite what some of the ill informed are claiming about what a vaccine is supposed to be, these remain wildly successful vaccines against Covid-19.
    2. The team confirmed elevated cases (above normal background) in 17-39 year olds of Myocarditis and Pericarditis by about 15-20 cases per million injections. Most cases were mild and resolved with over the counter medications, but no definition given of what "most cases" means.

    These data serve to cloud the discussion further concerning boosters for the US general population. If the vaccines remain so highly effective against severe disease and hospitalization, why get a booster? Previous data would suggest that a vaccinated person developing a mild to even moderate infection would have the most robust long term immunity to this virus?? This becomes even more interesting if some of the anti-viral treatments prove to really be effective at the end of the year.



    New data confirm Covid vaccines provide strong protection against hospitalization.
     
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  9. OklahomaGator

    OklahomaGator Jedi Administrator Moderator VIP Member

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    Thanks for all your contributions to this thread @ncargat1
     
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  10. ncargat1

    ncargat1 VIP Member

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    I am going to pat myself on the back here. I raised this very point a couple of weeks ago.

    Belgian researchers show that the Moderna shot afforded a significantly higher anti-body level than the Pfizer-BioNTech shots. One hypothesis is the difference in the volume of vaccine material in each shot. The Moderna shots were 2 shots at 100 micro-grams of vaccine, while the Pfizer treatment is 2 shots by 30 micro-grams.

    As a side note, the researchers also showed that the neutralizing antibodies were higher from the Moderna shot than infection as well.

    Moderna’s COVID-19 vaccine created more antibodies than Pfizer/BioNTech’s in study of vaccinated Belgian health-care workers
     
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  11. g8trjax

    g8trjax GC Hall of Fame

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    This is where my big problem lies with all these upcoming mandatory vaccine requirements and passports. Who is the ultimate arbiter and where/when does it all end?
     
  12. ncargat1

    ncargat1 VIP Member

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    Glaxo-Smith Kline and SK Bioscience are proceeding with their Covid19 vaccine candidate to Phase 3 trials. In Phase1/2 data, the vaccine titers showed neutralizing antibody levels 5-8x higher than those who recovered from infection.

    The vaccine is based on a self-assembled nano-particle in GSK's adjuvant. The vaccine nano-particle targets the receptor binding domain of the Spike protein.

    This type of vaccine would be a lower cost option than mRNA vaccines and would be more easily distributed around the world without extraordinary atmospheric controls.


    SK bioscience and GSK start Phase 3 trial of adjuvanted COVID-19 vaccine candidate | GSK
     
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  13. duchen

    duchen VIP Member

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    Replicates the Mayo Clinic study. Glad I got Moderna. probably explains why I had a 102 fever after the second Moderna vaccine.
     
  14. ncargat1

    ncargat1 VIP Member

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    In the US, the two mRNA shots are almost referred to interchangibly. However, I wonder if these data would convince the CDC and FDA at all to suggest that those who received the Pfizer shots may need a third shot while those who received the Moderna shot probably does not need it? Every time somone shows these sensationalized "breakthrough cases" it is almost always someone who has had the Pfizer shot?
     
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  15. duchen

    duchen VIP Member

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    That is an interesting question. Interesting to see the results of such a comparison, of there is one. But remember that Phizer came to market first. I know someone who was bedridden for 2 weeks after Moderna. One of the first Moderna shots given. He was exposed to Delta and a very high viral load.
     
  16. ncargat1

    ncargat1 VIP Member

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    Eh, I know nothing is 100%. I am still not sure that I need a booster if there is high probability of me only having minimal to moderate level symptoms. However, if there is booster in my future, I wonder if it should be the Moderna shot or the J&J shot to potentially broaden out my response vs just another Pfizer dose.
     
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  17. duchen

    duchen VIP Member

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    That is a good question. I know some folks who are considering mixing. I am going to stick with Modena for my booster when it is time. Pick the one with the strongest immune reaction to train the immune system.
     
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  18. slightlyskeptic

    slightlyskeptic All American

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    [​IMG]
     
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  19. ncargat1

    ncargat1 VIP Member

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    I hear you, but curious. Would concern be the credibility of the effectiveness data, the technology itself or the quality control of the manufacuring or both? There are some fantastic minds in China in the Bio and Medical fields.
     
  20. ncargat1

    ncargat1 VIP Member

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    Pfizer announced that they have started enrolling for their Phase 2/3 Covid19 anti-viral oral medication. This is only going to further infuriate the "Ivermectin or Die, it is all a Big Pharma Conspiracy" crowd because Merck announced that they also have started enrolling for Molnupiravir (Merck owns the patents on Ivermectin and has shown no interest in pursuing this medication as a Covid19 treatment) Phase3 trial. The NIH is already running a Phase3 trial, but Merck and Ridgeback have decided to go out and collect their own data as well.

    https://cdn.pfizer.com/pfizercom/20...hase_2_3.pdf?xngrygl6i_kDXWrJtM7ixP65qQ6ZXOK0

    Link to story about Merck Trial....
    Merck and Ridgeback Biotherapeutics Announce Initiation of Pivotal Phase 3 MOVe-AHEAD Study Evaluating Molnupiravir for Post-Exposure Prophylaxis of COVID-19 Infection | BioSpace