Covid-19: Treatments, Cures, and Vaccines

That sucks, in Volusia County they have the option as some kids are still doing distance learning.

 

We probably shouldn't laugh at Oklahoma
Florida ordered 1M doses of a Trump-touted drug. Hospitals didn't want it

 

We are doing distance learning as well, I just have to do both at the same time.

 

65? This virus is targeting mainly those over 75. Look at the average age of death of Covid. 65 is a lot different than 75 or 80. Look, it's ok that there are issues with the vaccine. We can't expect it to be perfect without having years to study the trials. Look at the NYT's claiming pregnant women have nothing to worry about with the vaccine.

Opinion | The False Rumors About Vaccines That Are Scaring Women

I know if my wife were pregnant there is zero chance i'd have her take the vaccine at this point. If a company didn't test it, then why let them get the vaccine? Nothing like being a guinea pig.

 

The worst possible way of meeting the needs of both those groups. I'm so disappointed in the state for not leveraging the already up and running FLVS program. They could have paused school for two weeks, taught all the teachers how to run an FLVS classroom and then given their online students a quality educational experience and their in person students whatever they could give them. But we chose to do it in the least effective way possible.

 

Vaccine Adverse Event Reporting System (VAERS) https://wonder.cdc.gov/vaers.html search on Pfizer/Moderna mRNA C19 vaccines for data available thru 1/15/21→ 149 deaths; 170 life-threatening events; 454 hospitalizations; & 1651 ER visits.

Just the data. If you go to the site here is the parameters I used.



Now these are not confirmed obviously. Just people reporting their symptoms. But I think having all the data available is useful when making decisions.

 

Just to be clear I said the first 1000 subjects were relegated to under 65 then opened up to no age limit, so out of 40000 people here are plenty of over 75 getting the vast majority of our subjects are over 70 because they can't get a "real vaccine" soon enough.

As far as expecting perfect that goes for EVERY MEDICATION. Look up Baycol studied for years, approved then years late it was found to have a higher than acceptable risk to liver/kidney damage.

I would never look at the NYT for facts about a medication.

One must weigh risk vs reward, I don't know if pregnancy increase morbidity and mortality in COVID so I can't evaluated the risk/reward.

Since kids haven't been tested yet and they have very low morbidity and mortality I don't plan on having my kids get vaccinated against COVID, but they also don't get the HPV/Flu shot either.

 

Causation vs correlation?

149 deaths out of how many vaccinated?
About 27 million in the US
That's 0.000000573%, pretty low assuming the vaccine CAUSED the death which is a very large assumption.

Look up incidence of adverse events for any vaccination? Are they different rates? I'd venture not.

ER visits is very vague, people are all worried about this vaccine and undoubtedly go to get check for any thing they are "worried about"

I had an employee today come show me their arm after a flu shot two days ago (3 cm black and blue mark), they were gonna go to the ER to get it checked...

 

You make it seem like i'm an anti vaxxer. I'm not. My mom got the Moderna vaccine a few weeks back and is scheduled to get her 2nd shot next week. But she's 80. We need to be getting the info on the adverse affects of the vaccine out there for people to make informed decisions. That's all i'm saying. And places like the NYT's is doing the drug companies work for them by saying there is nothing to fear in getting the shot. Reality is a healthy women of child bearing age has almost zero risk of dying of covid. And the issue is we have Teachers unions saying they aren't coming back to work until kids are vaccinated. That is insane.

 

I agree in principle, it just seemed like you were presenting incomplete info. That's all

 

Not incomplete. Just the data itself. And I stated these aren't verified, just reported.

 

no hpv vax for kids? disagree strongly on that one.

hope you don't plan on traveling with kids as the vaccine is likely going to be required for any intl travel.

 

Meanwhile, from the actual news pages.....

Novavax reports overall efficacy of 89.3% from its Phase 3 study of 40,000 in the UK, including 95.6% efficacy against the original strain and 85.6% efficacy against the so-called UK variant.

A parallel Phase 3 trial is being carried out in Mexico and the company expects that trial to be filled (30,000 participants) by mid-February.

A second Phase 2b trial carried out with those infected by the so-called "South African" variant, showed an efficacy of 60% in the HIV negative study participants and further drops to 49.4% in the small number with HIV.

Novavax COVID-19 Vaccine Demonstrates 89.3% Efficacy in UK Phase 3 Trial | Novavax Inc. - IR Site

 

One item I haven't seen discussed much is the relative risk reduction v. absolute risk reduction for the vaccine trials. The numbers are reported are relative risk reduction--which is definitely important. But as you move further away from the high risk people, absolute risk reduction should be considered as well. Below are stats from an article about the British leg. I'm assuming the placebo was 7,500 and vax group was 7,500

---The British trial involved 15,000 people aged 18 to 84, including 27% who were over the age of 65. The first interim analysis was based on 62 cases of confirmed COVID-19 among participants, of which 56 cases were observed in the placebo group versus six cases among people who received the vaccine.---

so 56/7,500=.00746667 risk of contracting COVID w/o Vaccine
and 6/7,500=.0008 risk of contracting COVID w/ vaccine

It's a great risk reduction if you contract COVID, but your overall risk-at least for this study was not very high to begin with. In the wild the risk of contracting COVID certainly seems higher, but it should be something a person considers.

In the article it mentions 27% of the british group was 65 and older. It will be interesting to see how many in that group contracted COVID.

FWIW-both my mother in law (2 pfizer doses) and mother (1 Moderna so far--waiting on 2nd) have been vaccinated and I get the flu vaccine every year. I'm in no way an anti-vaxxer

 

Absolute risk increases with time though, so while it's small during the very expedited study period, it'd get progressively higher as time goes on.

 

nope, its the same. Just need to make sure you get both doses from the same company

 

Has J&J done any studies to determine if 2 dosages would improve the effectiveness of the vaccine? Their current numbers are great compared to other vaccines but the bar was set high with Pfizer and Moderna

 

This. Absolute risk is time dependent

 

Johnson and Johnson files for Emergency Use Authorization. FDA sets meeting with advisory board for Feb 26th. They look to be able to supply 100 million doses by the end of June and are holding on to their claims of 1 billion doses before the end of the year.

Covid-19 Live Updates: Third U.S. Vaccine Moves Closer as Johnson & Johnson Seeks F.D.A. Green Light